The Parallel Unstructured Mesh Infrastructure (PUMI) provides geometric model interface and distributed mesh management to support automated adaptive simulation on massively parallel computers with high core count nodes. MeshAdapt performs parallel unstructured anisotropic adaptation of meshes, including high-order curved meshes, using local mesh modification to satisfy a prescribed anisotropic size field. ParMA performs efficient mesh multi-criteria partition improvement of PUMI meshes and has been used on meshes having up to 92 billion elements on 3/4 million cores.